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Autoimmune Bulbous Disease Care and Treatment

Why Choose Treatment for Autoimmune Bulbous Disease at University of Colorado Hospital?

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The dermatologists and staff at University of Colorado Hospital are trained to diagnose and treat all skin conditions, including different types of autoimmune bulbous disease.

UCH provides the highest levels of nonsurgical and surgical treatment using the latest techniques. Our nurses are certified in dermatology, oncology, surgery and wound care, helping ensure the best in patient care.

What is autoimmune bulbous disease?

In autoimmune diseases, the body's immune system response is misdirected toward the body's own cells.

Autoimmune bulbous (or bullous) disease describes three separate conditions that cause blisters on the skin: pemphigus, bullous pemphigoid, and dermatitis herpetiformis.

In severe cases, many blisters appear. These blisters can cause:

  • Itching
  • Rashes
  • Sores
  • Bleeding gums
  • Death (severe cases only)

The appearance of the blisters can be similar in these conditions, so a skin specialist must determine the underlying disease in order to provide proper treatment.

Tests & Treatments

Tests for Autoimmune Bulbous Disease

Your doctor may diagnose autoimmune bulbous disease by drawing blood.


The diagnosis may also require a skin lesion biopsy. During this procedure, your doctor removes a piece of skin and examines it to determine if you need further treatment. Sometimes the entire lesion has to be removed. A biopsy can usually be performed in the office with local anesthesia.


Treatments for Autoimmune Bulbous Disease

Treatments for autoimmune bulbous disease include:

  • Oral antibiotics
  • Niacin (a B complex vitamin), which helps the skin stay healthy. Niacin is usually given with the antibiotic tetracycline.
  • Anti-inflammatory drugs called corticosteroids, taken by mouth or injection or applied to the skin.

Your Medical Team

University of Colorado Hospital takes a team approach to autoimmune bulbous disease care. Doctors and nurses work specialists to provide the most appropriate care for each patient.


Autoimmune Bulbous Disease Specialists

  • Dermatologist – a doctor trained in the diagnosis and treatment of skin changes and diseases.
  • Family medicine doctor – a doctor trained to provide care for your entire family.


Other Autoimmune Bulbous Disease Staff

  • Registered nurse – a nurse licensed by the state who conducts medical evaluations, takes patient histories and provides care for patients with skin conditions.
  • Wound care specialist – a doctor or nurse trained to treat chronic and severe wounds

Patient Education

Living with Autoimmune Bulbous Disease

If unexplained blisters appear on your skin, it is important to see your doctor. Untreated blisters may cause skin infection. The blisters will often disappear if they are treated, although they may reappear after you stop.


Getting a Second Opinion about Autoimmune Bulbous Disease

The doctors and staff of the Dermatology team at University of Colorado Hospital are happy to provide second opinions for patients in the community.


Additional Autoimmune Bulbous Disease Resources

American Academy of Dermatology