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Exercise and Diabetes

Role of Vascular Funtion: Oxygen Delivery vs Oxygen Utilization in the Exercise Impairment in Type 2 Diabetes


COMIRB #: 06-0062

Study Purpose– This study will evaluate exercise function during single leg calf exercise in people with and without type 2 diabetes.


Study Design

  • Physical exam, blood draws, and activity questionnaire
  • Standardized diet before study visits
  • Assessment of body composition, insulin sensitivity, blood vessel function, cardiac function, and exercise capacity
  • Muscle biopsy of your calf
  • A two week supervised exercise training program


Study Duration

-          8 weeks or 2 months


Study Benefits – compensation will be provided for your time.  Lab tests will be made available to you at your request.


IRB Protocol Number

All Other Trials

  • Weight & Metabolism
  • Exercise
  • Bones, Joints, and Muscles
  • Diabetes
  • Heart & Circulation
Shawna McMillin at 303-724-2255
Eligibility and Other Participant Information

Study  Qualifications-

  1. Between 30 and 55 years old
  2. Be generally healthy, with or without type 2 diabetes (not using insulin)
  3. Be a non-smoker
  4. Currently exercise no more than once per week
  5. BMI less than < 23 or between 25 -40 (check your BMI at



  • University of Colorado Hospital (UCH)
    12605 E. 16th Ave.
    Aurora, CO 80045