The CABANA Trial has the overall goal of establishing the appropriate roles for medical and ablative intervention for atrial fibrillation (AF). The CABANA Trial is designed to test the hypothesis that the treatment strategy of left atrial catheter ablation for the purpose of eliminating atrial fibrillation (AF) will be superior to current state-of-the-art therapy with either rate control or rhythm control drugs for reducing total mortality in patients with untreated or incompletely treated AF.

The goal of the CASA study is to see if a new program for people with chronic heart failure improves symptoms, functioning, and quality of life. This new program helps people with common symptoms, including fatigue, shortness of breath, feeling down, sad or worried, and pain. The program also helps people adjust to medical illness and provides resources to family caregivers. The program integrates this care into ongoing chronic illness care. No experimental drugs or devices are being tested.

Cardiovascular Safety of Exenatide Once Weekly (Type 2 Diabetes)

A prospective multicenter imaging study for evaluation of chest pain. Objective is to determine whether an initial non-invasive anatomic imaging strategy with coronary CT angiography (CTA) will improve clinical outcomes in subjects with symptoms concerning for coronary artery disease relative to an initial functional testing strategy (usual care).