Restoration of microRNAs: a form of differentiation therapy for treatment of aggressive breast cancers

Objective

The purpose of this study is to learn more about genetic material in cells called micro RNAs (miRNAs). miRNAs are increasingly being discovered as having an important role in cancer growth. We believe a specific miRNA called miR-200, may cause breast cancer to be less invasive and more sensitive to common breast cancer chemotherapies such as paclitaxel.

IRB Protocol Number

10-0734

Principal Investigator(s)

VIRGINIA BORGES

Cancer Trials

• Breast Cancer

Sponsor(s)

UCCC

Contact

ELIZABETH MANTHEY at 720-848-8031
or ELIZABETH.MANTHEY@UCDENVER.EDU

Eligibility and Other Participant Information

What To Expect : A small sample of fresh tissue will be obtained during the time of your surgery. // Eligibility criteria : Women who have had less than a complete response after being treated with neoadjuvant chemotherapy can join this study. You must be over the age of 18.